Notes
Slide Show
Outline
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“ Creating a Competitive Advantage for
Life Science Companies in
South Carolina”
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Charter
  • Statewide program to
  •  (1) develop emerging life science companies and support (2) recruitment of biotech companies to South Carolina.


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SC Bio Vision
  • Develop incubator system
  • Virtual biotech company structure
  • Support creation of required infrastructure
  • Expand life science research
  • Foster creation of 20,000 new jobs


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Retaining the Best and Brightest
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Biotechnology Update
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What is Biotechnology
  • Technology based on life sciences
    • 130 drugs and vaccines
    • Hundreds medical diagnostic kits
    • Environmental products
    • Agricultural and food products
    • New chemicals, enzymes
    • Textiles, pulp & paper
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Industry Statistics
  • Doubled total product sales since 1996
  • Doubled total revenues since 1996
  • Patents/Yr.  1996 = 4,600  2000 = 14,000
  • New drug approvals 20 – 32/year
  • Average per employee salary $50,000 NC
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Product Examples
  • Human Growth Hormone
  • TPA
  • Detergent enzymes
  • Transgenic pigs
  • Transgenic tobacco
  • Bio-pesticides
  • Peptide production
  • Veterinary products
  • Animal  feed supplements
  • EPO
  • Implant Devices
  • Hemoglobin
  • Sepsis
  • T-Cell Lymphoma
  • Textiles
  • Biochemicals
  • Vaccines
  • HIV Diagnostics
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Market Capitalization
Billion Dollars
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Biotech Company Revenues
Billion Dollars
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Biotech Private and Public Companies
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Biotechnology Employment
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Biotech Industry Financing
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5-7 Year Industry Trends
  • Commercialization / Manufacturing
  • Greenfield opportunities in the SE
  • Diversification outside of pharmaceuticals
    • Agricultural
    • Chemical/Environmental
  • International Programs (Europe & Asia)
  • Good IPO market
  • Equity market returning to biotechnology
    • Pharmaceuticals/biotechnology


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Implications for South Carolina
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Life Science in South Carolina
  • Changing economy post NAFTA and development of international markets
    • Impact of GATT 2005, European Union
    • Mexico, China, CBI, Puerto Rico 936
  • NAFTA and South Carolina
  • Importance of research/technology based economies


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Legislative Activities
  • Life Science Act
  • Venture Capital Act
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Why All of South Carolina Can Participate
  • Transgenic tobacco in Florence
  • Transgenic trees in Charleston
  • Natural protein textile research
  • Bioterrorism vaccines in Charleston
  • Industrial enzymes in Kingstree
  • Clinical trials across South Carolina
  • Biopharmaceutical companies in Sumter
  • Combinatory chemistry Rock Hill
  • Contract manufacturing in Charleston






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The Monitor Study
  • Chemicals (Biotechnology/Life Sciences)
  • Automotive
  • Textile
  • Tourism
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Why SC for Recruiting and Developing Biotechnology
  • Natural resources for manufacturing.
  • History of international companies.
  • Mobile technology.
  • Tax environment (Additional pending legislation).
  • Unique resources and qualifications each research institution.
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 Enhancing Competitive Position
  • Endowed chairs program.
  • Research collaborations SC research institutions.
  • Commercialization (66% R&D companies).
  • Recruitment (34% Manufacturing companies).
  • Biotechnology image.



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Implications for The University of South Carolina
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USC Resources Combinatory Chemistry & Life Sciences
  • Combinatory Chemistry/protein chemistry
  • PEG Genisys
  • Public Health Services
  • USC Medical School
  • Oncology Research
  • Pending Research Park
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Life Science Opportunities
  • Savannah River Plant/Nuclear Medicine
    • Isotopes linked to unique receptors
    • Diagnostics
  • Expand Transgenic Plant Research
  • Increase Medical Research
    • VA related medical research
    • CNS, vaccines, trauma/battle related
  • Expand USC Clinical Trial Program


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Path Forward for USC
  • Expand endowed chairs in life sciences.
  • Establish new life science companies.
  • Develop lab incubator.
  • Create image of life science research center.
  • Increase Palmetto Biotechnology Alliance involvement.


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South Carolina Biotechnology Research Institutions
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Is the Juice Worth the Squeeze
  • Field of operation review (patents)
  • Ability to finance
  • Competitor review
  • Manufacturing model
  • Confidential review
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SC Bio
  • Karl Kelly: CEO
  • Christine Schwartz: Research Manager
  • Scott Davis: Manager Development Services
  • Ashley Hannah:  Manager Communications and Marketing Services
  • Rick Moseley: Facility Engineer/Safety Officer
  • USC, Lander, Citadel: (5) Research Assistants



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SC Bio
Governing Board

    • USC
    • Clemson
    • MUSC
    • Greenwood Genetic Center


    • SCRA
    • SC Dept of Commerce
    • Steven L. Jones
    • Greenwood Economic Alliance
    • GMI


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Technical and
Business Consulting Services
    • Company formation/structure
    • Executive recruitment
    • Financing
    • Product development and clinical trials
    • Manufacturing concept development
    • Marketing and sales agreements

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Industry Advisory Board
  • Genentech
  • Amgen
  • Merck
  • Roche Carolina
  • DSM Biologics
  • Savient Pharmaceuticals
  • MetaMorphix
  • Diversa
  • Aradigm
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What Makes
SC BIO Unique?
  • Process/Product Development
  • Speed to market
  • Venture recognition of product development
  • “SC can get product in market faster than all other states.”


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Research Assistant Projects
  • General Research
    • Science review
    • Literature search
    • Competitor information
    • Patent search
    • PBA support
    • SC Bio PR program
    • Recruitment support



  • Special Projects
    • Patent evaluation
    • Mfg model
    • Financing plan
    • Marketing strategy
    • Executive summary
    • Business plan
    • Presentations
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SC BIO
Target Companies
  • Transgenic Plants
  • Biomaterial Textiles
  • Protein Chemistry
  • Pegulation
  • Genetic Diagnostics
  • Oncology
  • Animal Research Models
  • Peptide Drug Delivery
  • BAC Library Development Services



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Why South Carolina Can Compete
  • History in recruitment
  • Ability to attract funding
  • Research capabilities
  • Business environment
  • Leadership commitment
  • Livability
  • Water
  • Effective electrical costs
  • Favorable permit environment
  • Existing companies
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Commitment to South Carolina
  • “This program creates new companies and jobs in South Carolina.  These new companies will carry the Palmetto State into direct competition with the centers of innovation and development around the world while quietly raising the standard of living at home.”
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